James Marsden and Thomas Middleditch will lend their voices to animated comedy Henchmen.

The duo are joined by Rosario Dawson, Alfred Molina and Nathan Fillion, according to Entertainment Weekly.

Jane Krakowski, Rob Riggle, Craig Robinson and Will Sasso have also been cast.

Silicon Valley's Middleditch will star as Lester, who joins the Union of Evil and is assigned to a crew of workers which includes Stew (Robinson), Jane (Krakowski) and fallen henchman Hank (Marsden).

After the group survive a shift working for The Gluttonator (Will Sasso), they are sent to work at the Vault of Villainy, where Lester accidentally steals the 'ultimate weapon'.

Meanwhile, the evil Baron Blackout (Molina) and his henchman Biff (Riggle) are determined to defeat their nemesis Captain Superior (Fillion) - a situation which causes a whole host of problems.

Hank soon finds himself in an impossible situation - if he wants to save his team and his love Jolene (Dawson), he will have to break his 'risk nothing' code and become the very thing he hates: a hero.

The movie, based on a short, is being directed and co-written by Adam Wood, with David Ray and Jay D Waxman joining him on the writing team.