According to NorthAmericanWrestlingRankings.blogspot.com, [which started keeping track of wrestlers’ records and ranking them as of Nov. 2006], when The Miz lost to Roman Reigns on the 8/22/14 episode of Smackdown it was his 100th televised singles loss.
The Miz is just the 4th wrestler to lose 100 matches [behind only Dolph Ziggler, Jack Swagger, and Kofi Kingston] and just the 3rd to register triple digit wins AND losses [Dolph and Kofi being the others]. Others closing in on the century mark for losses as of 8/22/14 are: Zack Ryder [92] and Randy Orton [90].
[NOTE: these records count t.v. and ppv singles matches since Nov. 2006 ONLY].