Bill Murray plays a nightmare neighbour in the first St Vincent trailer.
The legendary actor stars alongside Melissa McCarthy, Chris O'Dowd and Naomi Watts in Ted Melfi's comedy.
The film centres around Vincent, an ageing and broke bachelor whose antagonistic behaviour has left him alone in the world.
When a new neighbour (McCarthy) moves in next door, he forms an unlikely bond with her young son (Jaeden Lieberher).
Murray was most recently seen in The Grand Budapest Hotel and The Monuments Men. He will not be returning for the planned Ghostbusters sequel.
McCarthy will next be seen in Tammy, which arrives in cinemas this week.
St Vincent will be released in the US on October 24. A UK release date is yet to be announce